Web8.7 Renal Impairment. Alfentanil injection should be administered with caution to patients with kidney dysfunction because of the renal excretion of alfentanil and its metabolites. … Web- Alfentanil is metabolised in the liver and its inactive metabolites are renally excreted, making it an appropriate alternative to morphine in patients with severe renal impairment. - It has a rapid analgesic effect and short duration of action (1-2 hours) which limits it use
HIGHLIGHTS OF PRESCRIBING INFORMATION - Pfizer
WebMay 14, 2008 · This was done in a comparative study of 10 adult ICU patients with normal or mildly impaired renal function and 30 patients with moderate or severe renal impairment with a mean creatinine clearance of 14.7 ml/minute [15, 30]. All patients received remifentanil for up to 72 hours, with the dosage starting with 0.1 to 0.15 μg/kg per minute. WebOct 19, 2024 · arrhythmia, slow or fast heart rate, blurred vision, dizziness, and. postoperative sleepiness. Seek medical care or call 911 at once if you have the following … timmy meredith
Reference ID: 4027961 - Food and Drug Administration
WebAlfentanil CLINICAL USE Opioid analgesic: Short surgical procedures Intensive care sedation DOSE IN NORMAL RENAL FUNCTION ; IV injection: Spontaneous respiration: … WebFeb 2, 2024 · Alfentanil may cause bradycardia which can be severe with rapid onset. This can be antagonised by atropine. Care should be taken when alfentanil is administered … WebFeb 9, 2024 · Includes Alfentanil indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. ... Renal impairment: Use with caution in patients with renal impairment. timmy mia schedule