Cap-gly domain containing linker protein
WebJan 26, 2024 · Background: CAP-Gly domain containing linker protein family member 4 (CLIP4) plays an important role in cancers. However, its expression, prognostic value, and biological effect in breast cancer remain unclear. Methods: Data on patients diagnosed with breast cancer were retrieved from the TCGA-BRCA and other public omics databases. WebThe protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body.
Cap-gly domain containing linker protein
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WebMar 21, 2016 · CLIP3 (CAP-Gly Domain Containing Linker Protein 3) is a Protein Coding gene. Among its related pathways are TNF signaling and p75 NTR receptor-mediated signalling . Gene Ontology (GO) annotations related to this gene include microtubule binding and ganglioside binding . An important paralog of this gene is CLIP4. WebJan 26, 2024 · The CAP-Gly domain, which is conserved among organisms, is a small 80-residue protein module (Riehemann and Sorg, 1993). CAP-Gly domains are important …
WebMar 5, 2024 · CLIP1 CAP-Gly domain containing linker protein 1 Gene ID: 6249, updated on 5-Mar-2024 Gene type: protein coding Also known as: RSN; CLIP; CYLN1; CLIP170; CLIP-170 See all available tests in GTR for this gene Go to complete Gene record for CLIP1 Go to Variation Viewer for CLIP1 variants Summary WebJan 15, 2024 · Cytoplasmic linker protein 170 (CLIP170) is a CAP-Gly domain-containing protein that is associated with the plus end of growing microtubules and implicated in various cellular processes, including the regulation of microtubule dynamics, cell migration, and intracellular transport.
WebFeb 5, 2024 · CLIP4 CAP-Gly domain containing linker protein family member 4 [ (human)] Gene ID: 79745, updated on 5-Feb-2024 Summary Predicted to enable microtubule plus-end binding activity. Predicted to be involved in cytoplasmic microtubule organization. Located in intracellular membrane-bounded organelle.
WebCAP-Gly domain-containing linker protein 1-like Status UniProtKB unreviewed (TrEMBL) Organism Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi) Amino acids 2185 Protein existence Predicted Annotation score 1/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function …
WebClip1 CAP-GLY domain containing linker protein 1 [ (Norway rat)] Gene ID: 65201, updated on 4-Nov-2024 Summary Enables microtubule plus-end binding activity. Involved in positive regulation of dendrite development. Located in cytoplasmic microtubule and microtubule plus-end. charles tyrwhitt poplin vs twillWebOur findings define the molecular basis of CAP-Gly domain function, including the tubulin detyrosination-tyrosination cycle. They further establish fundamental roles for the interaction between CAP-Gly proteins and C-terminal EEY/F sequence motifs in regulating complex and dynamic cellular processes. Publication types charles tyrwhitt reviews redditWebJul 20, 2015 · The predicted nonhelical C- and N-terminal domains of the homodimeric protein are connected by a long coiled-coil domain. Pierre et al. (1992)identified a novel … harsed hiralal chimaWebThe CLIP2 gene provides instructions for making a protein called CAP-Gly domain containing linker protein 2. The protein is also known as CLIP-115. This protein is found … charles tyrwhitt schuheWebEight key genes were identified: heat shock 70 kDa protein 4 (HSPA4), cell division cycle associated 7 (CDCA7), cell division cycle 20 (CDC20), cyclin-dependent kinase 1 (CDK1), CAP-GLY domain containing linker protein 1 (CLIP1), cyclin B1 (CCNB1), H2A histone family, member X (H2AFX), and Bloom syndrome, RecQ helicase-like (BLM). charles tyrwhitt review shirtsWebCAP-Gly domain-containing linker protein 2 is a protein that in humans is encoded by the CLIP2 gene. [5] [6] [7] The protein encoded by this gene belongs to the family of … harsens island newspaperWebGastric cancer (GC) is the fifth most common cancer and the third leading cause of cancer-associated mortality worldwide. In the current study, comprehensive bioinformatic analyses were performed to develop a novel scoring system for GC risk assessment based on CAP-Gly domain containing linker protein family member 4 (CLIP4) DNA methylation status. harse v pearl life assurance