Human placental lactogen (hPL), also called human chorionic somatomammotropin (hCS), is a polypeptide placental hormone, the human form of placental lactogen (chorionic somatomammotropin). Its structure and function are similar to those of human growth hormone. It modifies the metabolic state of the … See more hPL molecular mass is 22 125 Da and contains single chain consisting of 191 amino acid residues that are linked by two disulfide bonds and the structure contains 8 helices. A crystal structure of hPL was determined by See more hPL is present only during pregnancy, with maternal serum levels rising in relation to the growth of the fetus and placenta. Maximum levels are reached near term, typically to 5–7 mg/L. Higher levels are noted in patients with multiple gestation. Little hPL enters … See more • Placental lactogen in other species • Somatotropin family See more • Speroff L, Glass RH, Kase NG (1999). Clinical gynecologic endocrinology and infertility (Sixth ed.). Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-683-30379-1 See more hPL affects the metabolic system of the maternal organism in the following manners: • See more While hPL has been used as an indicator of fetal well-being and growth, other fetal testing methods have been found to be more reliable. Also, normal pregnancies have been reported with undetectable maternal levels of hPL. See more • Human+Placental+Lactogen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more WebJul 9, 2014 · Function Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. 1 publication Miscellaneous CSH2 sequence only differs from CSH1 sequence in 1 aa. Features Showing features for binding site. Expand table
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WebAlso called chorionic somatomammotropin, hPL is a single-chain, nonglycosylated polypeptide composed of 191 amino acid residues and two disulfide bridges, with a molecular mass of 21,600 Da. 46 It is closely related chemically and biologically to both GH (85% amino acid homology) and prolactin (13% amino acid homology). WebMar 4, 2024 · The Human Chorionic Somatomammotropin (hCS) hormone is produced by the placenta during pregnancy. It is an important hormone for maintaining the pregnancy, as it helps to stimulate the growth of the maternal tissues that will support the fetus during its development. tines for troy built pony tiller
(PDF) Evidence for human placental lactogen immunoreactivity in …
WebProduct Specs; Item Recombinant Human Chorionic Somatomammotropin Hormone 1 (placental lactogen); Company Creative BioMart; Price Supplier Page View Company Product Page; Catalog Number CSH1-346H; Species Human; Source/Expression System E. coli; Purity >95% by SDS-PAGE and >95% by HPLC; NCBI Full Gene Name chorionic … Webchorionic somatomammotropin sheep placental insufficiency iugr Goals / Objectives The placenta mediates fetal growth and development, and placental insufficiency results in fetal growth restricted livestock that have impaired lifelong productivity, including poor feedlot performance as well as reduced carcass quality and fertility. WebFeb 2, 2024 · The objective was to determine the effect of inducing an accessory corpus luteum (CL) using GnRH or human chorionic gonadotropin (hCG) on the day of in vitro-produced (IVP) embryo transfer (ET) on pregnancy per ET (P/ET) and calving/ET in dairy heifers and lactating cows. Dairy heifers (11-15 mo of … party store silverdale wa