2024 Cisplatin and hypokalemia

Cisplatin and hypokalemia

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August undefined, 2024

WebDec 9, 2024 · When hypokalemia is secondary to tumor activity, treating the cancer is necessary, in addition to symptomatic therapy for hypokalemia, in order to prevent the recurrence of symptoms. Patients with carcinoid syndrome should receive somatostatin analog in order to inhibiting hormonal hyper-secretion and improve symptoms [ 136 ] . WebMar 4, 2024 · He completed three cycles of neoadjuvant dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin (dd-MVAC), which was complicated by multiple gastrointestinal (GI) symptoms of nausea, vomiting, resultant hypokalemia, and cytopenia, but he was able to successfully undergo definitive robot-assisted laparoscopic radical …

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WebJul 24, 2024 · Cisplatin, a chemotherapeutic drug, can also cause hypocalcemia through hypomagnesemia. Foscarnet can cause hypocalcemia by forming complexes with ionized calcium, thereby … WebJun 1, 2024 · Hypomagnesemia and hypokalemia are side effects of certain chemotherapies, including cisplatin, cetuximab, eribulin, and ifosfamide. When patients concurrently receive chemotherapy and take medications that cause hypomagnesemia or hypokalemia, electrolyte imbalances are amplified. fieldin culbreth iv

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WebNational Center for Biotechnology Information WebMay 18, 2024 · Impaired kidney function is a relatively common complication of amphotericin B, as are other kidney manifestations, including urinary potassium wasting and hypokalemia, urinary magnesium wasting and hypomagnesemia, metabolic acidosis due to type 1 (or distal) renal tubular acidosis (RTA), and polyuria due to nephrogenic diabetes … WebDigitalis therapy may exaggerate metabolic effects of hypokalemia, especially myocardial effects. All patients receiving LASIX therapy should be observed for these signs or symptoms of fluid or ... There is a risk of ototoxic effects if cisplatin and LASIX are given concomitantly. In addition, nephrotoxicity of nephrotoxic drugs such as ... grey rock narcissism

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Cisplatin and hypokalemia

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WebApr 1, 2024 · Triple disorder with metabolic alkalosis, metabolic acidosis, and respiratory alkalosis Compensated metabolic alkalosis Analyzing an acid-base disturbance is a 5-step process. Step 1: Look at the pH. Our patient’s arterial pH was 7.55, which, being higher than 7.45, shows a state of alkalemia. WebCisplatin is a common cause of hypomagnesemia and hypokalemia due to renal magnesium (Mg) and potassium (K) losses. Magnesium plays an important role in the …

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WebApr 12, 2024 · AKI-related cisplatin may also be associated with tubulopathies, such as Fanconi-like syndrome, hypomagnesemia, salt-loosing syndrome and distal renal tubular acidosis . Tubular dysfunction is characterized by electrolyte disorders such as hyponatremia, hypokalemia and hypomagnesemia. WebNov 24, 2024 · fast, slow, or irregular heartbeat. headache (sudden and severe) hives, itching, skin rash. inability to speak. nervousness. noisy breathing. pain or discomfort in the arms, jaw, back, or neck. pounding in the ears. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue.

WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative … WebMar 24, 2024 · Case 1: A case of hyponatremia following cisplatin chemotherapy A 64 year-old man with small cell lung cancer was treated with cisplatin chemotherapy with etoposide and concurrent chest radiotherapy. Serum sodium was 137 mmol/L prior to initiation of chemotherapy.

WebHypokalemia may develop with furosemide, especially with brisk diuresis, inadequate oral electrolyte intake, when cirrhosis is present, or during concomitant use of corticosteroids, ACTH, licorice in large amounts, or prolonged use of laxatives. ... There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly. In ... WebThe Radiation Therapy Oncology Group launched a phase III trial to test the hypothesis that adding cetuximab to the radiation-cisplatin platform improves progression-free survival (PFS).Patients and methodsEligible patients with stage III or IV HNC were randomly assigned to receive radiation and cisplatin without (arm A) or with (arm B) cetuximab.

WebJul 15, 2015 · Alterations in serum electrolytes including hypomagnesemia, hypokalemia, hyponatremia, hypocalcemia, and hypophosphatemia have been reported in studies evaluating various doses of cisplatin.

Webis a major concern when prescribing cisplatin. Renal dysfunction due to cisplatin may manifest as renal insufficiency, hypokalemia and hypomagnesemia. The risk for these … field in computinghttp://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf field in crmWebAug 1, 2004 · Nephrotoxicity after cisplatin administration usually manifests as increased serum creatinine and blood urea nitrogen (BUN) levels, as well as electrolyte … greyrock mountain coloradoWebMar 25, 2024 · The most common laboratory findings include: hyponatremia, hyperkalemia, and anemia [ 4 ]. Hydrocortisone is the mainstay of treatment, and fludrocortisone is added to replace mineralocorticoid deficiency. Usually, hydrocortisone doses are divided into two or three doses, with the highest dose in the morning to mimic the circadian rhythm. fieldin culbreth umpireWebFirst-line multiagent chemotherapy comprises doxorubicin, cisplatin, and high-dose methotrexate (MAP regimen) . ... Regarding toxicity, rash and hypokalemia was the most common grade 3 adverse event, and one death from end organ failure was reported that was possibly related to the drug. fieldin culbreth retiresWebDec 17, 2024 · Hypokalemia is defined as a serum or plasma potassium that is less than the normal value. Most reference laboratories establish the lower pediatric limit of normal … field indenticalWebKey Points. When evaluating hypokalemia, use the history to explore possible losses (renal vs. GI), shifts (pH, insulin, etc.), and intake. Get a full medication history. Then use the … field in computer