WebMar 21, 2024 · Disabled Homolog 2, Mitogen-Responsive Phosphoprotein3 Dab, Mitogen-Responsive Phosphoprotein, Homolog 23 External Ids for DAB2 Gene HGNC: 2662 NCBI Entrez Gene: 1601 Ensembl: ENSG00000153071 OMIM®: 601236 UniProtKB/Swiss-Prot: P98082 Previous GeneCards Identifiers for DAB2 Gene GC05M039550 GC05M040463 … WebThe tumor suppressor DAB2IP (Disabled homolog 2 interacting protein), also known as AIP1 (ASK1 interacting protein), has an important role in this context, as it modulates signal transduction by multiple inflammatory cytokines and growth factors. DAB2IP is a Ras-GAP, and negatively controls Ras-dependent mitogenic signals.
798492 - Gene Resultrasal3 RAS protein activator like 3 [ (zebrafish)]
WebOrthologous to human DAB2IP (DAB2 interacting protein). [provided by Alliance of Genome Resources, Apr 2024] dab2ipb DAB2 interacting protein b [ (zebrafish)] Gene ID: 558237, updated on 4-Nov-2024 Summary Predicted to enable GTPase activator activity. WebDec 10, 2016 · Varicella-zoster virus (VZV) induces abundant autophagy. Of the nine human herpesviruses, the VZV genome is the smallest (~124 kbp), lacking any known inhibitors of autophagy, such as the herpes simplex virus ICP34.5 neurovirulence gene. Therefore, this review assesses the evidence for VZV-induced cellular stress, endoplasmic-reticulum … reajustar imagen
Thioredoxin-Interacting Protein as a Novel Potential Therapeutic …
WebOct 15, 2024 · In this study, we demonstrate that in OCSC, the tumor suppressor disabled homolog 2-interacting protein (DAB2IP) is silenced by EZH2-mediated H3K27 trimethylation of the DAB2IP promoter. CRISPR/Cas9-mediated deletion of DAB2IP in epithelial ovarian cancer cell lines upregulated expression of stemness-related genes … WebJun 6, 2024 · Studies have shown that miR-556-3p can regulate dab2ip and promote tumor deterioration, and up-regulation of BIM inhibits CRC cell progression. However, the … WebApr 14, 2024 · Histone acetylation plays a vital role in organizing chromatin, regulating gene expression and controlling the cell cycle. The first histone acetyltransferase to be identified was histone acetyltransferase 1 (HAT1), but it remains one of the least understood acetyltransferases. HAT1 catalyzes the acetylation of newly synthesized H4 and, to a … dupro projects