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Disabled homolog 2-interacting protein

WebMar 21, 2024 · Disabled Homolog 2, Mitogen-Responsive Phosphoprotein3 Dab, Mitogen-Responsive Phosphoprotein, Homolog 23 External Ids for DAB2 Gene HGNC: 2662 NCBI Entrez Gene: 1601 Ensembl: ENSG00000153071 OMIM®: 601236 UniProtKB/Swiss-Prot: P98082 Previous GeneCards Identifiers for DAB2 Gene GC05M039550 GC05M040463 … WebThe tumor suppressor DAB2IP (Disabled homolog 2 interacting protein), also known as AIP1 (ASK1 interacting protein), has an important role in this context, as it modulates signal transduction by multiple inflammatory cytokines and growth factors. DAB2IP is a Ras-GAP, and negatively controls Ras-dependent mitogenic signals.

798492 - Gene Resultrasal3 RAS protein activator like 3 [ (zebrafish)]

WebOrthologous to human DAB2IP (DAB2 interacting protein). [provided by Alliance of Genome Resources, Apr 2024] dab2ipb DAB2 interacting protein b [ (zebrafish)] Gene ID: 558237, updated on 4-Nov-2024 Summary Predicted to enable GTPase activator activity. WebDec 10, 2016 · Varicella-zoster virus (VZV) induces abundant autophagy. Of the nine human herpesviruses, the VZV genome is the smallest (~124 kbp), lacking any known inhibitors of autophagy, such as the herpes simplex virus ICP34.5 neurovirulence gene. Therefore, this review assesses the evidence for VZV-induced cellular stress, endoplasmic-reticulum … reajustar imagen https://groupe-visite.com

Thioredoxin-Interacting Protein as a Novel Potential Therapeutic …

WebOct 15, 2024 · In this study, we demonstrate that in OCSC, the tumor suppressor disabled homolog 2-interacting protein (DAB2IP) is silenced by EZH2-mediated H3K27 trimethylation of the DAB2IP promoter. CRISPR/Cas9-mediated deletion of DAB2IP in epithelial ovarian cancer cell lines upregulated expression of stemness-related genes … WebJun 6, 2024 · Studies have shown that miR-556-3p can regulate dab2ip and promote tumor deterioration, and up-regulation of BIM inhibits CRC cell progression. However, the … WebApr 14, 2024 · Histone acetylation plays a vital role in organizing chromatin, regulating gene expression and controlling the cell cycle. The first histone acetyltransferase to be identified was histone acetyltransferase 1 (HAT1), but it remains one of the least understood acetyltransferases. HAT1 catalyzes the acetylation of newly synthesized H4 and, to a … dupro projects

High expression of disabled homolog 2-interacting …

Category:Dab2ip disabled 2 interacting protein [ (house mouse)]

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Disabled homolog 2-interacting protein

DAB2IP Plays Important Clinical Significance and Correlates With …

WebSep 26, 2024 · Orthologous to human DAB2IP (DAB2 interacting protein). [provided by Alliance of Genome Resources, Apr 2024] Other designations. disabled homolog 2-interacting protein, ASK-interacting protein 1, ASK1-interacting protein 1, DAB2-interacting protein, DOC-2/DAB-2 interactive protein, disabled 2 interacting protein … WebFeb 19, 2024 · The protein-protein interactome of disabled homolog 2 interacting protein (DAB2IP) in the context of copy number alterations in triple-negative breast cancer (TNBC). SWAN was used to generate this diagram.

Disabled homolog 2-interacting protein

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WebThe protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. WebDisabled homolog 2-interacting protein is a protein that in humans is encoded by the DAB2IP gene. DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that …

WebFeb 19, 2024 · Suppression of one master regulator has now been shown by Xiong et al. to directly enable TNBC cells to establish tumours in mice with fewer cells while also better … Webdisabled homolog 2-interacting protein. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. DAB2IP DAB2 interacting protein [] Gene ID: 104688508, updated on 21-Dec-2024. Summary. Other designations. disabled homolog 2-interacting protein ...

WebJan 1, 2024 · PH_DAB2IP; DOC-2/Disabled homolog 2-interacting protein Pleckstrin homology (PH) domain pfam12004 Location: 618 → 1122 DUF3498; Domain of … WebFeb 11, 2024 · Disabled Homolog 2-Interacting Protein (DAB2IP) status is one of the major factors involved in sensitivity to chemotherapy in multiple cancer types. In the present study, we aimed to investigate the potential roles of DAB2IP in GC cell proliferation and cisplatin resistance.

WebBackground: Disabled homolog 2-interacting protein (DAB2IP), a Ras GTPase-activating protein, is downregulated in several cancers. Its depletion is involved in tumor cell …

Webdisabled homolog 2-interacting protein. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. DAB2IP DAB2 interacting protein [] Gene ID: 106495996, updated on 2-Sep-2024. Summary. Other designations. disabled homolog 2-interacting protein ... dupsko gummiWebID: PAIP2_MOUSE DESCRIPTION: RecName: Full=Polyadenylate-binding protein-interacting protein 2; Short=PABP-interacting protein 2; Short=PAIP-2; Short=Poly(A)-binding protein-interacting protein 2; FUNCTION: Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is … du prvačinaWebConclusion: An increased expression of DAB2IP in AAA tissues was shown. We suggest 2 potential mediators of DAB2IP expression in abdominal aortic aneurysm, EZH2 and mir-363-3p. Keywords: Abdominal aortic aneurysm (AAA); Disabled homolog 2-interacting protein (DAB2IP); EZH2; miR-363-3p. du province\u0027sWebDisabled homolog 2-interacting protein. Gene. DAB2IP. Source organism. Homo sapiens (Human) go to search. UniProt. A0A3B3ITG3 go to UniProt. Experimental structures. None available in the PDB. Biological function. Catalytic activity: undefined go to … duproprio st jerome condoWebSep 30, 2024 · Disabled homolog 2 interacting protein (DAB2IP) is a member of the Ras GTPase-activating protein family located at chromosome 9q33.1–q33.3, which negatively regulates the Ras-mediated signaling pathway through interacting with the N-terminal domain of the DAB2 protein ( 6 ). reajuste ipva 2023 rjWebDab2ip DAB2 interacting protein [ (Norway rat)] Gene ID: 192126, updated on 23-Jun-2024 Summary Other designations disabled homolog 2-interacting protein, ASK-interacting protein 1, DOC-2/DAB2 interactive protein, DOC2/DAB2 interactive protein GeneRIFs: Gene References Into Functions reajuste jeepWebDisabled homolog 2-interacting protein can be a novel clinical biomarker for patients with renal cell carcinoma, which also provides new insights for the future treatments of … reajuste do salario minimo no governo bolsonaro