WebMar 26, 2024 · The transcription of bacterial genes driven by DNA-dependent RNA polymerase (RNAP) is the first step in gene expression. Holo RNAP consists of multi-subunit, catalytic core enzyme, formed by the α 2 ββ ′ ω subunits, and the sigma (σ) subunit, which confers the promoter selectivity of the RNAP. Bacteria usually contain …
Mutational Analysis of an Extracytoplasmic-Function Sigma Factor …
WebMay 22, 2024 · Although the RNAP core is catalytically competent for RNA synthesis, the selectivity of transcription initiation requires a sigma (σ) factor for promoter recognition and opening. Expression of alternative σ factors provides a powerful mechanism to control the expression of discrete sets of genes (a σ regulon) in response to specific ... WebThe transcription of bacterial genes driven by DNA-dependent RNA polymerase (RNAP) is the first step in gene expression. The RNAP core is a large, complex enzyme consisting of the subunits α2ββ´ω. The additional sigma (σ) subunit (factor), which binds to the RNAP core to form the RNAP holoenzyme, is responsible for promoter recognition and … safe wa qr code download
Sigma Factor - an overview ScienceDirect Topics
Websigma factor activity ISM . Inferred from Sequence Model Term mapped from: InterPro:PF08281. ECO:0000259 match to InterPro signature evidence used in automatic assertion: Biological Process GO:0006355 regulation of transcription, DNA-templated ISM . Inferred from Sequence Model ... WebExtracytoplasmic function (ECF) sigma factors are subunits of the RNA polymerase specialized in activating the transcription of a subset of genes responding to a specific environmental condition. The signal-transduction pathways where they participate can be activated by diverse mechanisms. The most common mechanism involves the action of a … WebMetal-responsive RNA polymerase extracytoplasmic function (ECF) sigma factors Mol Microbiol. 2024 Aug ... In this review, we have focused on the metal-responsive ECF … the yetties band