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Herc3

Witryna6 lip 2024 · HERC3 can increase the protein and phosphorylation levels of p53, which further promotes apoptotic activity. In a xenograft mouse model, the effect was obtained in a treatment group that combined … WitrynaIn the present study, we identified a novel E3 ligase, HERC3, which can mediate ubiquitination of MM1 and promote its proteasome-dependent degradation. We found …

ΔNp63α down-regulates c-Myc modulator MM1 via E3 ligase …

Witryna21 sty 2024 · And HERC3 could regulate epithelial-mesenchymal transition (EMT) in CRC. Furthermore, immunoprecipitation (IP), coimmunoprecipitation (co-IP) and GST … WitrynaTroligt E3 ubiquitin-proteinligas HERC3 är ett enzym som hos människor kodas av HERC3- genen .Genen är en medlem av HERC-familjen av ubikitinligaser och kodar ett protein med en HECT-domän och en RCC1- liknande domän (RLD). Det binder ubiquitin och hPLIC-1/2 via sin HECT-domän. Alternativt kryddade transkriptionsvarianter som … tayla thomas age https://groupe-visite.com

Functional and pathological relevance of HERC family

Witryna22 cze 2024 · HERC proteins are ubiquitin E3 ligases of the HECT family. The HERC subfamily is composed of six members classified by size into large (HERC1 and … Witryna12 sty 2001 · The presence of a HECT domain in HERC3 suggests that it may bind ubiquitin. To check this possibility, we performed pull-down experiments with GST … WitrynaProtein names. Recommended name. Probable E3 ubiquitin-protein ligase HERC3. EC number. EC:2.3.2.26 ( UniProtKB ENZYME Rhea) Alternative names. HECT … the druid\u0027s prayer michele mclaughlin

Gene: HERC3 (ENSG00000138641) - Summary - Homo_sapiens

Category:HERC3 binding to and regulation by ubiquitin - ScienceDirect

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Herc3

Gene: HERC3 (ENSG00000138641) - Summary - Homo_sapiens

WitrynaCowley, M., Wood, A. J., Böhm, S., Schulz, R., & Oakey, R. J. (2012). Epigenetic control of alternative mRNA processing at the imprinted Herc3/Nap1l5 locus. WitrynaOur HERC3 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the HERC3 antibody that fits your needs. Choose from 1 of 7 HERC3 antibodies, …

Herc3

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WitrynaHERC3 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, HERC3 Genome Browser, HERC3 References. HERC3 - Explore an overview of … WitrynaHERC3 directly binds to β-TrCP, blocks its interaction with YAP/TAZ, and thus prevents YAP/TAZ ubiquitination and degradation. Expression levels of HERC3 correlate with …

WitrynaHERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide … WitrynaDownload scientific diagram HERC3 reduces NF- ␬ B DNA-binding by limiting its nuclear import. ( A ) BAEC were transfected with control vector or myc-HERC3, stimulated for 0, 0.5 or 1 h with ...

WitrynaHERC3 Gene. HERC3. Name. HECT and RLD domain containing E3 ubiquitin protein ligase 3. Description. This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. WitrynaID: HERC3_HUMAN DESCRIPTION: RecName: Full=Probable E3 ubiquitin-protein ligase HERC3; EC=6.3.2.-; AltName: Full=HECT domain and RCC1-like domain …

WitrynaHERC3-001: 4974: 1050aa: ENSP00000385684.1 . Gene/transcipt that contains an open reading frame (ORF). Protein coding. CCDS34028: B4DK41 C9J6Z1 C9J8E7 C9JFL2 C9JKA7 D6RAT5 F5GWU0 Q15034 Q4W5H5: NM_014606.2: The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative …

Witryna11 lip 2012 · For example, Herc3 is abundantly expressed in the piriform cortex relative to expression of Nap1l5 ( 26), and this may enable biallelic expression of full-length … the drum awards for pr 2023Witryna北京博奥龙免疫技术有限公司是由留学归国人员创办的生命科学领域技术研发型企业,通过自主创新的品牌产品改变传统实验模式,使研究变得更轻松、更高效。服务涵盖抗原抗体,HPV-L1抗原抗体,Plant actin 单抗,β-tubulin单抗、GAPDH单抗、α-tubulin单抗、β-actin单抗等,咨 the drumhead star trekWitrynaTo our knowledge, the biological roles of HERC3 remain elusive at present. Our results illustrate the biological function of HERC3 E3 ubiquitin ligase for the first time. Importantly, the results that IL-6 and TNF-α can mediate HERC3-dependent ubiquitination enrich our understanding of the regulation of E3 ubiquitin ligase activity. tayla weightmanWitrynaHERC3-001: 4974: 1050aa: ENSP00000385684.1 . Gene/transcipt that contains an open reading frame (ORF). Protein coding. CCDS34028: B4DK41 C9J6Z1 C9J8E7 C9JFL2 … the drum lab laguna hillsWitrynaHERC3 on the contrary is a cytoplasmic protein (Figure 2 and (17, 19)) that affects NF-κB before it enters the nucleus. Interestingly, HERC3 binding and subsequent RelA … tayla whatmoreWitrynaHERC3 negatively regulates NF-kappaB signaling by enhancing RelA subunit degradation. we found somatic mutations of HERC2, HERC3, TRIP12, UBE2Q1 and … the drum and monkey solihullWitrynaherc3 : herc3 属于参与膜转运活动的 e3 泛素连接酶家族。herc3 与 hplic-1 和 hplic-2 相互作用,位于晚期内体和溶酶体。 herc4 : herc4 属于参与膜转运活动的 e3 泛素连接 … tayla wilson model