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The human lysosome gene database

WebApr 12, 2013 · The Human Lysosome Gene Database (hLGDB) is the first resource that provides a comprehensive and accessible census of the human genes belonging to the … WebLysosome-associated membrane protein 2 ( LAMP2 ), also known as CD107b ( C luster of D ifferentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins . The protein encoded by this gene is a member of a family of membrane glycoproteins.

The awesome lysosome EMBO Molecular Medicine

WebThe LAMP2 gene provides instructions for making a protein called lysosomal associated membrane protein-2 (LAMP-2), which, as its name suggests, is found in the membrane of cellular structures called lysosomes. Lysosomes are compartments in the cell that digest and recycle materials. The role the LAMP-2 protein plays in the lysosome is unclear. Some … WebJun 25, 2009 · Fig. 1 A regulatory gene network controlling the expression of lysosomal genes. (A) Genomic distribution of CLEAR elements (red dots) at human gene … disney vacation club resort https://groupe-visite.com

National Center for Biotechnology Information

WebAll lysosomal genes and 12 breast cancer-related genes aligned to identify the most similar genes to breast cancer-related genes. Different centralities were applied to score each human... WebCELL LINE TYPES. The 1055 different cell lines used in the Cell Line section have been selected to represent various cell populations in different tissue types and organs of the human body. Most of the cell lines used are human cancer cell lines (n = 985). In addition to the cancer-derived cell lines, there is a number of cell lines that have ... Web17 rows · Mar 27, 2024 · The Human Gene Database. GeneCards is a searchable, integrative database that provides comprehensive, user-friendly information on all annotated and … disney vacation club resorts for sale

Identifying Key Lysosome-Related Genes Associated with …

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The human lysosome gene database

The gene for the lysosomal protein LAMP3 is a direct target of the ...

WebApr 12, 2024 · We explored the effect of thrombin on human aortic smooth muscle cells (HASMCs) and further analyzed its role in the pathogenesis of atherosclerosis (AS). Thrombin-induced differentially expressed genes (DEGs) in HASMCs were identified by analyzing expression profiles from the GEO. Subsequently, enrichment analysis, GSEA, PPI … WebJan 19, 2016 · The expanding role of the lysosome in human diseases. Mutations in genes encoding proteins involved in lysosomal function cause lysosomal storage diseases (LSDs), a group of about 50 inherited disorders characterized by the progressive accumulation of undegraded substrates inside the lysosome. Patients with LSDs present with a …

The human lysosome gene database

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Web8 rows · Apr 12, 2013 · The Human Lysosome Gene Database (hLGDB) is the first resource that provides a comprehensive and ... WebFeb 1, 2007 · It is reported that the gene encoding the Drosophila ortholog of the HPS5 subunit of BLOC‐2 is identical to the granule group gene pink (p), which was first studied in 1910 but had not been identified at the molecular level. Lysosome‐related organelles comprise a group of specialized intracellular compartments that include melanosomes …

WebThe Lysosome Gene Database is an ongoing effort to catalogue genes encoding lysosomal proteins. For each lysosomal gene, LGDB provides information on miRNA-genes interactions. Filter genes View only genes reported lysosomal by of the following sources: Proteomics Studies (view) - 5 out of 5 selected ( select all none)

WebAug 26, 2024 · The genes profiled were those reported on the Human Autophagy Database 39 and Human Lysosome Gene Database 40, as well as PD risk genes, which have been … WebThe expression of genes was determined with Illumina Human HT-12 V3 bead chips (Illumina, San Diego, CA, USA). In order to estimate significantly differentially expressed …

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WebHowever, the low methylation levels of the two methylated sites in the LAPTM5 gene was closely ... which was involved in negative regulation of B and T cell receptor on the cell surface via facilitating lysosome degradation. 12,13 ... et al. DiseaseMeth version 2.0: a major expansion and update of the human disease methylation database. ... cpa exam view scoresWeb15 rows · LYSOSOME: Systematic name: M13845: Brief description: Genes annotated by the GO term GO:0005764. ... cpa fairview tnWebAfter gaining access to the endo-lysosomal pathway, several viruses depend on lysosomal cathepsin proteases to cleave their structural proteins triggering productive entry. Targeting of cathepsins and other luminal lysosomal proteins to lysosomes requires their modification with mannose 6-phosphate (M6P) signals. Key to M6P tagging is N-acetylglucosamine … disney vacation club resorts wiki